T-cell proliferation was abrogated by oxaliplatin treatment. T-cell proliferation assay was performed with lymph node cells from DBA/1 mice immunized with ovalbumin (OVA) Oxaliplatin was added to the cell culture and the proliferation was measured. Oxaliplatin suppressed the proliferative response in a dose-dependent manner when compared with controls.
Östberg et al. Arthritis Research & Therapy 2008 10:R1 doi:10.1186/ar2347