TLR2 and TLR4 mRNA expression in PBMCs and PMNs from patients with BD. Expression levels in peripheral blood mononuclear cells (PBMCs) of (a) Toll-like receptor (TLR)2 and (b) TLR4 mRNA in healthy controls (HC), and patients with active and inactive Behçet's disease (BD) were determined semiquantitatively by real-time PCR. Horizontal bars represent mean values of HO-1 mRNA. Expression levels in polymorphonuclear leukocytes (PMNs) of (c) TLR2 and (d) TLR4 in HC, and patients with active and inactive BD. *P < 0.05, **P < 0.01, as determined using the Kruskal-Wallis test with post-hoc Scheffe's test. AU, arbitrary unit; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; NS, not significant.
Kirino et al. Arthritis Research & Therapy 2008 10:R16 doi:10.1186/ar2367