|
Haplotype frequencies and RA susceptibility |
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| Haplotype |
IL-13 haplotypes |
IL-4 haplotypes |
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|
|
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| SNP1 |
SNP2 |
RA |
Controls |
OR (95% CI) |
P |
SNP3 |
SNP4 |
SNP5 |
RA |
Controls |
OR (95% CI) |
P |
|
|
|
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| 1 |
C |
G |
0.754 |
0.747 |
1.00 |
- |
C |
G |
G |
0.760 |
0.766 |
1.00 |
- |
| 2 |
T |
A |
0.110 |
0.107 |
1.02 (0.82–1.26) |
0.86 |
A |
G |
C |
0.136 |
0.128 |
0.89 (0.65 – 1.23) |
0.49 |
| 3 |
C |
A |
0.065 |
0.078 |
0.83 (0.63–1.09) |
0.19 |
A |
C |
G |
0.090 |
0.091 |
1.38 (1.00 – 1.91) |
0.96 |
| 4 |
T |
G |
0.068 |
0.067 |
1.02 (0.77–1.35) |
0.91 |
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|
The frequency of haplotypes in each control is shown. SNP1 is rs1800925, SNP2 is rs1295686, SNP3 is rs2227284, SNP4 is rs2243263, and SNP5 is rs2243267. CI, confidence interval; OR, odd ratio; RA, rheumatoid arthritis; SNP, single nucleotide polymorphism. | |||||||||||||
Marinou et al. Arthritis Research & Therapy 2008 10:R80 doi:10.1186/ar2454 |
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