Figure 1.

Linkage disequilibrium plot of the STAT1-STAT4 region in a Japanese population and first screening of 52 tag single nucleotide polymorphisms (SNPs). In the upper panel, P values for differences in allele frequencies were calculated by chi-square test using two-by-two contingency tables. The -log P value for each SNP is shown. In the lower panel, r2 values calculated using Haploview version 4.0 software based on data from 102 healthy individuals are shown. The location and direction of transcription of STAT1 and STAT4 are indicated by arrows. SNPs rs10168266, rs11889341, and rs7574865 belong to the same haplotype block.

Kawasaki et al. Arthritis Research & Therapy 2008 10:R113   doi:10.1186/ar2516
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