Figure 2.

The domain structures of an antibody molecule and its derivatives. (a) An antibody molecule. (b) A fragment antigen-binding (Fab) fragment. (c) A non-covalently linked VH and VL domains (Fv). (d) A single-chain Fv. (e) A receptor-immunoglobulin fusion protein. CH, heavy chain constant domain; CL, light chain constant domain; Fc, fragment crystallisable; VH, heavy chain variable domain; VL, light chain variable domain.

Isaacs Arthritis Research & Therapy 2009 11:225   doi:10.1186/ar2594
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