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Open Badges Letter

Ultrasound has the potential to detect degeneration of articular cartilage clinically, even if the information is obtained from an indirect measurement of intrinsic physical characteristics

Hiroshi Kuroki1, Yasuaki Nakagawa2*, Koji Mori3, Masahiko Kobayashi4, Ko Yasura4, Yukihiro Okamoto4, Takashi Suzuki4, Kohei Nishitani4 and Takashi Nakamura4

Author Affiliations

1 Division of Motor Function Analysis, Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan

2 Department of Orthopaedic Surgery, National Hospital Organization Kyoto Medical Center, Kyoto, 612-8555, Japan

3 Department of Applied Medical Engineering Science, Graduate School of Medicine, Yamaguchi University, Ube, Yamaguchi, 755-8611, Japan

4 Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan

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Arthritis Research & Therapy 2009, 11:408  doi:10.1186/ar2727

See related research by Nakagawa et al.,, and related editorial by Zhang and Huang,

Published: 24 June 2009

First paragraph (this article has no abstract)

We appreciate the concern shown by Zheng and Huang [1] regarding our earlier article [2]. We presented simple data showing that the ultrasound response of articular cartilage may be related to its International Cartilage Repair Society grading, and concluded that ultrasound evaluation using the signal intensity – dependent on the ultrasound reflection coefficient at the cartilage surface – may be helpful to differentiate International Cartilage Repair Society grades, especially grade 0 from grade 1 cartilage [2].