Effect of antioxidants on reactive oxygen species (ROS) generation. Blood mononuclear cells (BMCs) of representative fibromyalgia (FM) patients were treated with 10 μmol/L CoQ10, 30 μmol/L α-tocopherol (α-toc), and 10 μmol/L N-acetylcysteine (N-Acet) for 24 h. Data represent the mean ± SD of three separate experiments. *P < 0.001 between controls and FM patients; **P < 0.005 between the absence or presence of CoQ10 and α-toc treatment.
Cordero et al. Arthritis Research & Therapy 2010 12:R17 doi:10.1186/ar2918