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A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis

Susan K Wallis, Laura A Cooney, Judith L Endres, Min Jie Lee, Jennifer Ryu, Emily C Somers and David A Fox*

Arthritis Research & Therapy 2011, 13:R15  doi:10.1186/ar3239