Percentages of CCR4+CCR6+ T-helper, regulatory T and Fox-P3-positive cells in peripheral blood mononuclear cells. Statistical multiple bar graphs showing percentages of increased CCR4+CCR6+ T-helper (Th) cells, reduced regulatory T (Treg) cells and reduced forkhead box P3 (Fox-P3)-positive cells in the peripheral blood mononuclear cells (PBMCs) of patients with ankylosing spondylitis (ASp), compared with values for healthy donors (HLA-B27-negative healthy donors (HD1) and HLA-B27-positive healthy donors (HD2)). *P < 0.001, Student's t test for independent data.
Wu et al. Arthritis Research & Therapy 2011 13:R29 doi:10.1186/ar3257