Effect of OP-1 on BMP-2 gene expression. Real time PCR of in vitro verification experiments, where knee chondrocytes cultured in monolayers were treated for 48 hours with 100 ng/ml recombinant OP-1. The graph illustrates an inhibition of BMP-2 mRNA expression.
Chubinskaya et al. Arthritis Research & Therapy 2011 13:R55 doi:10.1186/ar3300