Table 3

Renal manifestations of systemic diseases commonly seen by rheumatologists


Renal manifestation

Rheumatoid arthritis

Mesangial GN, renal amyloidosis, membranous GN

Spondylarthropathy/psoriasis arthritis

Renal amyloidosis, IgA nephropathy

Systemic lupus erythematosus

Lupus nephritis: proliferative immune complex GN, membranous GN

Sjögren's syndrome

Interstitial nephritis with renal tubular acidosis (type 1)

ANCA vasculitis

Crescentic (pauci-immune) GN, interstitial nephritis

Giant cell arteritis

Renal artery stenosis

Immune complex disease

Immune complex GN

Diffuse cutaneous systemic scleroderma

Scleroderma renal crisis, crescentic GN (with myeloperoxidase ANCA), interstitial nephritis, chronic (ischemic) kidney disease


Nephrocalcinosis, nephrolithiasis, granulomatous interstitial nephritis


Nephrotic syndrome (membranous GN, minimal change disease, focal glomerulosclerosis)


Chronic kidney disease: diabetic nephropathy


Chronic kidney disease: hypertensive nephropathy

ANCA, anti-neutrophil cytoplasmic antibody; GN, glomerulonephritis.

Anders and Vielhauer Arthritis Research & Therapy 2011 13:222   doi:10.1186/ar3256