Polarization of T cells and B cells within the salivary gland inflammatory response. Naïve B cells (B0) polarized in the presence of T helper (Th)1 cells are designated B effector (Be)1 cells. Naïve T cells (Th0) polarized in the presence of Be2 cells are designated Th2 cells. Consequently, interconnections exist between the B-cell and T-cell cytokine networks. TGF, transforming growth factor; T Reg, regulatory T cell.
Youinou and Pers Arthritis Research & Therapy 2011 13:227 doi:10.1186/ar3348