Immunoglobulin (Ig) levels in all six patients, across the study period. A) IgG, reference range (RR) 5.65 to 17.65 g/l, < 3 g/l represented study discontinuation threshold; B) IgA, RR 0.7 to 4 g/l; C) IgM, RR 0.4 to 2.3 g/l. IgA and IgM were not measured during the screening period (Days-14 to 1). Discontinuation days were not necessarily scheduled follow-up days. LLN, lower limit of normal; ULN, upper limit of normal.
Ginzler et al. Arthritis Research & Therapy 2012 14:R33 doi:10.1186/ar3738