CX3CL1 and CX3CR1 expressions in lung with ILD in polymyositis patients. Lung specimens from (A, B, G, H) controls and (C to F and I to L) polymyositis (PM) patients with ILD were stained with anti-CX3CL1 mAb (A, C, E), anti-CX3CR1 antibody (G, I, K), or isotype-matched control antibodies (B, D, F, H, J, L). Arrows indicate the positive infiltrated mononuclear cells (I), alveolar macrophages (M), vascular endothelial cells (V), and epithelial cells (E). Original magnification, ×400.
Suzuki et al. Arthritis Research & Therapy 2012 14:R48 doi:10.1186/ar3761