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Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity

YK Onno Teng*, Gillian Wheater, Vanessa E Hogan, Philip Stocks, EW Nivine Levarht, Tom WJ Huizinga, Rene EM Toes and Jacob M van Laar

Arthritis Research & Therapy 2012, 14:R57  doi:10.1186/ar3770

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