Corticosteroid treatment does not affect clinical signs of spontaneous arthritis. (A) Cumulative incidence of arthritis and (B) clinical severity score in dexamethasone-treated and control animals (n = 10 and 12 animals per group, respectively). (C) Dexamethasone treatment does not affect histological severity of arthritis (ns: P = 0.2). Data in (B) and (C) are shown as mean ± SEM. (D) Effect of dexamethasone treatment on different features of ankylosing enthesitis. Data in (D) are shown as percentage of affected paws exhibiting a specific treat compared to the total number of affected paws. ns, nonsignificant; SEM, standard error of the mean.
Braem et al. Arthritis Research & Therapy 2012 14:R59 doi:10.1186/ar3772