Decreased frequency of naïve T cells (TN) and unreduced frequency of very early memory T cells (TVEM) in patients with granulomatosis with polyangiitis (GPA). Percentages of CCR7+CD45RAmed TVEM and CCR7+CD45RAhigh TN in the CD4+ T cell population are shown. Percentages of positive cells were assessed by flow cytometry. Values are presented as mean ± standard error of the mean. **P < 0.01, Mann-Whitney U test. CCR, CC chemokine receptor; HC, healthy control.
Fagin et al. Arthritis Research & Therapy 2012 14:R73 doi:10.1186/ar3794