Resolution:
## Figure 2.
Effect of collagen-induced arthritis induction and statin treatment on body weight. Mice were immunized at day 0, challenged at day 21, and weighed three times a week
until euthanasia at day 42. Statins were given daily. Black circles connected by dotted
line, atorvastatin before collagen-induced arthritis (CIA) induction; black squares
connected by dotted line, atorvastatin after CIA induction; black triangles connected
by dotted line, pravastatin before CIA induction; black inverted triangles connected
by dotted line, pravastatin after CIA induction; black diamonds connected by dotted
line, CIA control; black circles connected by continuous line, negative control. n = 12 per group. The effect of arthritis induction was assessed using an independent-samples
t test; the effect of statin treatments was assessed using one-way analysis of variance,
followed by the Bonferroni post hoc test.
Vandebriel |