Additional file 4.

Figure S4. Modulation of TGase activity is associated with TG2 regulation. (A-C) TGase activity was measured by using in situ 5-(biotinamido)-pentylamine incorporation assay in (A) C-FLSs or A-FLSs cultured on gelatin matrix. (B) A-FLSs were transfected with control- or TG2-shRNA-expressing lentivirus. (C) C-FLSs were incubated with TGF-β (20 ng/ml), DTT (1 mM), or cystamine (100 μΜ).

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Lauzier et al. Arthritis Research & Therapy 2012 14:R159   doi:10.1186/ar3899