Additional file 1.

FcγR expression on synovial and blood neutrophils and on monocytes in properdin-deficient mice with CAIA. (A) FcγR was expressed on blood wild-type Ly6G+ cells but not on properdin-deficient cells, as shown in one individual experiment. Frequencies of Ly6G+ FcγR+ in blood at day 10 of disease are presented on the graph. Data are expressed as the mean ± SD of the positive cells from three experiments involving four mice/group; *P < 0.05; ***P < 0.001; Student t test. (B) Elevated numbers of CD14+ FcγR+ cells in blood of KO CAIA mice are shown on the graph. Data represent the mean ± SD of positive cells from three experiments involving five mice/group. *P < 0.05; **P < 0.01; and ***P < 0.001; Student t test. (C) FcγR expression was found on synovial neutrophils from arthritic properdin-deficient and wild-type mice. The histograms are representative of three separate experiments and show the analyses of the synovial cell pool from five mice/group.

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Dimitrova et al. Arthritis Research & Therapy 2012 14:R173   doi:10.1186/ar3926