Additional file 2.

Figure S2. Effects of mevalonate on the statin-induced suppression of RANKL. FLSs from RA patients (patients 1, 2, and 3) were cultured in the presence of TNF-α (20 ng/ml), and then simvastatin (50 to 100 μM) and mevalonate (100 μM) were added for 24 hours. RANKL expressions were analyzed with RT-PCR (A) and Western blotting (B).

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Kim et al. Arthritis Research & Therapy 2012 14:R187   doi:10.1186/ar4018