In vitro glucocorticoid sensitivity is associated with clinical glucocorticoid therapy outcome in rheumatoid arthritis
1 Department of Internal Medicine, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, Rotterdam, 3015 CE, The Netherlands
2 Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, Rotterdam, 3015 CE, The Netherlands
3 Department of Rheumatology, Maasstad Hospital, Maasstadweg 21, Rotterdam, 3079DZ, The Netherlands
4 Department of Rheumatology, Sint Franciscus Gasthuis, Kleiweg 500, Rotterdam, 3045PM, The Netherlands
Arthritis Research & Therapy 2012, 14:R195 doi:10.1186/ar4029Published: 24 August 2012
Additional file 1:
Table S1. Primer and probe sequences for GILZ, IL-2, and HPRT. This table gives the sequences of the primers and probes used in the bioassay to measure messenger RNA levels of GILZ, IL-2, and HPRT.
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Additional file 2:
Figure S2. Bivariate correlations between in vitro parameters of glucocorticoid sensitivity. This figure displays how different in vitro parameters of GC sensitivity, as measured in the bioassay and GC-binding assay, correlate to each other.
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Additional file 3:
Table S3. DAS and individual measures of the DAS in tREACH and FLARE patients. This table provides detailed information on DAS and individual measures of the DAS in the different subsets of studied patients, both at baseline and after 2 weeks of GC treatment.
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