Additional file 1.

Kinetics of matrilin-3 (MATN3)-induced IL-1Ra gene expression in human chondrocytes. A figure showing MATN3 stimulation of IL-1Ra gene upregulation by C28/I2 cells and primary human chondrocytes (PHCs) in the absence (A, C) and presence of IL-1β (B, D). Cells were treated with 0, 100 or 200 ng/ml of recombinant human MATN3 protein. IL-1β was used at a concentration of 5.0 ng/ml. *P ≤ 0.05 for statistically significant differences relative to the 0 ng/ml treatment group, for each respective time point. Individual experiments were done in biological triplicate.

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Jayasuriya et al. Arthritis Research & Therapy 2012 14:R197   doi:10.1186/ar4033