ChIP of the IGFBP-3 gene promoter. HepG2 cells, either untreated (U) or treated (T) with small interfering RNA directed against HMGA1, were used for ChIP of the IGFBP-3 gene by using a polyclonal antibody against HMGA1. There were three separate experiments. ChIP, chromatin immunoprecipitation; HMGA1, high-mobility group A1; IGFBP-3, insulin-like growth factor binding protein 3.
Gasparini et al. Arthritis Research & Therapy 2012 14:R207 doi:10.1186/ar4045