Weekly LS mean sleep quality score. Weekly assessment analyses based on the results of the MMRM analysis with weekly mean sleep quality score defined as the mean of the last seven daily diary sleep quality ratings. Scores range from 0 to 10 with higher scores indicating decreased sleep quality. Mean value (± SE) shown for each week, where ***P ≤0.0001 for each treatment time point compared with placebo.
Ohta et al. Arthritis Research & Therapy 2012 14:R217 doi:10.1186/ar4056