Plasma mannose binding lectin (MBL) levels in systemic lupus erythematosus (SLE) patients and healthy controls (HCs). (A) Plasma samples from HCs (n = 67) and SLE patients (n = 93) were quantified by ELISA according to the manufacturer's instructions. SLE patients displayed significantly higher concentrations of MBL compared to HCs (P < 0.0001). (B) Based on clinical and biochemical parameters, SLE patients were further categorized as musculoskeletal or cutaneous (MC) (n = 16), neuropsychiatric systemic lupus erythematosus (NPSLE) (n = 26), carditis (n = 14), autoimmune hemolytic anemia (AHIA) (n = 10), serositis (n = 18), nephriris (n = 52), pneumonitis (n = 11) and MBL levels were compared among them. Dots represent individual samples; bars show the mean ± SD. The Student's t-test was used to compare MBL concentrations among clinical categories.
Panda et al. Arthritis Research & Therapy 2012 14:R218 doi:10.1186/ar4057