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Open Access Highly Accessed Open Badges Research article

Matrix to predict rapid radiographic progression of early rheumatoid arthritis patients from the community treated with methotrexate or leflunomide: results from the ESPOIR cohort

Bruno Fautrel1*, Benjamin Granger1, Bernard Combe2, Alain Saraux3, Francis Guillemin4 and Xavier Le Loet5

Author Affiliations

1 Université Pierre et Marie Curie (UPMC) - Paris 6, GRC-08 EEMOIS; AP-HP Pitié Salpêtrière Hospital, Department of Rheumatology, 75013 Paris, France

2 Montpellier I University; Department of Rheumatology, Lapeyronie Hospital, UMR 5535, 34000 Montpellier, France

3 Brest University; Department of Rheumatology, La Cavale Blanche University Hospital, 29000 Brest, France

4 Lorraine University, Paris-Descartes University, EA 4360 APEMAC -- Inserm, CIC-EC CIE6, CHU de Brabois, 54505 Vandoeuvre-lès-Nancy, France

5 Rheumatology Department, Rouen University Hospital & INSERM U905, Institute for Research and Innovation in Biomedicine, Rouen University; 76031 Rouen, France

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Arthritis Research & Therapy 2012, 14:R249  doi:10.1186/ar4092

Published: 19 November 2012

Additional files

Additional file 1:

Supplemental figures. Figure S1: Cumulative plot of the vSHS score variation between baseline and month 12. Figure S2: Fit of the final model estimated by receiver operating characteristic curve analysis. Figure S3: Observed patient frequencies in the different cells of the ESPOIR matrix.

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