Effect of Link N on proteoglycan deposition by mesenchymal stem cells (MSCs) in chondrogenic differentiation medium. (A) Alcian blue staining of proteoglycan in extracellular matrix after MSCs were cultured in chondrogenic differentiation medium without (control) or with Link N for 21 days. (B) The absorbance value of the solubilized Alcian blue at 620 nm. The results are shown as mean ± SD of three independent experiments with MSCs from three different donors.
Antoniou et al. Arthritis Research & Therapy 2012 14:R267 doi:10.1186/ar4113