Table 2 

Adipokines in lean, overweight and obese patients 

Lean (group 1) 
Overweight (group 2) 
Obese (group 3) 
Comparison of groups 



Baseline 
∆15 wks 
∆30 wks 
Baseline 
∆15 wks 
∆30 wks 
Baseline 
∆15 wks 
∆30 wks 
Groups 
At baseline 
Change after 15 weeks 
Change after 30 weeks 

Median (range) 
Median (range) Pvalue^{a} 
Median (range) Pvalue^{a} 
Median (range) 
Median (range) Pvalue^{a} 
Median (range) Pvalue^{a} 
Median (range) 
Median (range) Pvalue^{a} 
Median (range) Pvalue^{a} 
Pvalue^{b} 
Pvalue^{b} 
Pvalue^{b} 



Adiponectin ng/ml 
18620.8 (5707.0 to 23038.0) 
783.3 (3501.6 to 4270.7) 
488.5 (1047.7 to 6069.1) 
4580.4 (2939.7 to 9634.0) 
400.0 (438.0 to 1681.0) 
578.0 (1764.5 to 1281.3) 
4745.5 (2864.9 to 5879.0) 
1011.3 (382.6 to 3273.8) 
1206.9 (1157.4 to 3811.5) 
Lean vs overweight 
0.013 
0.591 
0.346 
n = 9 
P = 0.441 n = 9 
P = 0.398 n = 7 
n = 26 
P = 0.122 n = 25 
P = 0.861 n = 25 
n = 13 
P = 0.133 n = 13 
P = 0.214 n = 9 
Lean vs obese 
0.003 
0.794 
1.000 

Leptin ng/ml 
16012.4 (10250.4 to 25627.3) 
2136.2 (4133.4 to 5400.4) 
4455.8 (10473.7 to 2250.7) 
27658.2 (19222.8 to 45504.1) 
1417.0 (6055.4 to 6858.3) 
1760 (9912.1 to 9778.1) 
45300.0 (34456.5 to 86307.4) 
5269.7 (5534.8 to 9055.5) 
1446.4 (3059.4 to 8129.1) 
Lean vs overweight 
0.067 
0.939 
0.161 
n = 9 
P = 0.515 n = 9 
P = 0.128 n = 7 
n = 26 
P = 0.778 n = 25 
P = 0.443 n = 25 
n = 13 
P = 0.422 n = 13 
P = 0.594 n = 9 
Lean vs obese 
<0.001 
0.471 
0.142 

NPY pg/ml 
114.5 (86.6 to 624.6) 
19.0 (10.7 to 98.5) 
6.7 
122.8 (80.5 to 164.9) 
7.7 (27.4 to 31.3) 
9.0 (8.2 to 27.3) 
113.7 (76.0 to 553.8) 
21.8 (1.3 to 225.0) 
44.4 (18.3 to 1272.7) 
Lean vs overweight 
0.82 
0.178 
0.824 
n = 4 
P = 0.465 n = 4 
P = 0.18 n = 2 
n = 16 
P = 0.959 n = 16 
P = 0.256 n = 15 
n = 6 
P = 0.075 n = 6 
P = 0.043 n = 5 
Lean vs obese 
0.914 
0.762 
0.095 

Resistin pg/ml 
14768.2 (12312.3 to 27191.5) 
927.7 (3165.5 to 3897.5) 
1006.1 (8555.9 to 4448.6) 
14419.1 (13786.6 to 16531.2) 
437.3 (1698.2 to 2634.9) 
701.1 (573.9 to 3872.6) 
14951.6 (12671.2 to 20016.0) 
1189.2 (1110.2 to 2292.4) 
3110.7 (534.1 to 4311.0) 
Lean vs overweight 
0.67 
1.000 
0.789 
n = 9 
P = 0.678 n = 9 
P = 1.000 n = 7 
n = 26 
P = 0.465 n = 23 
P = 0.051 n = 25 
n = 13 
P = 0.221 n = 13 
P = 0.214 n = 9 
Lean vs obese 
0.794 
0.845 
0.837 



Serum levels of adiponectin, leptin, NPY and resistin at baseline (0 weeks), change (∆) during training (15 weeks) and change after training (30 weeks). Median values and interquartile range are indicated. ^{a}Wilcoxon signed rank test. ^{b}MannWhitney Utest. NPY, neuropeptide Y. 

Bjersing et al. Arthritis Research & Therapy 2013 15:R34 doi:10.1186/ar4187 