Association between clinical improvement (change in Ankylosing Spondylitis Disease Activity Score) and immunogenicity. Change in Ankylosing Spondylitis Disease Activity Score (delta-ASDAS) measured 6 months after switching in spondyloarthritis patients who presented or not anti-drug antibodies (ADA) against the first anti-TNF. Data shown as interquartile ranges (p75, upper edge; p25, lower edge; p50, midline of the box).
Plasencia et al. Arthritis Research & Therapy 2013 15:R79 doi:10.1186/ar4258