Figure 2.

Decreased ability to degrade NETs affects 41% of the SLE patients. A-B. The ability of serum to degrade NETs compared to internal control of serum from 77 healthy controls (A) and 69 patients with SLE followed during multiple time points (B). Dashed line indicates cut-off for "normal" and "decreased" degradation. C. The fraction of all time points for which patients, who at least once displayed a decreased ability to degrade NETs, had a decreased NET degrading ability. Quantiles are displayed in gray with a median of 20% and mean of 34% (not shown). NETs, neutrophil extracellular traps; SLE, systemic lupus erythematosus

Leffler et al. Arthritis Research & Therapy 2013 15:R84   doi:10.1186/ar4264
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