Least squares mean changes from baseline in additional efficacy outcomes. Least squares mean changes and standard errors from randomization at weeks 2, 4, 8 and 12 of double-blind treatment (visits 4, 5, 6 and 7), with the last observation carried forward. BPI = Brief Pain Inventory; FIQR = Revised Fibromyalgia Impact Questionnaire; LS = least squares; SF-36 = Short Form-36 Health Survey; VAS = Visual Analogue Scale. *P < 0.05; **P < 0.01; ***P < 0.001 versus placebo.
Clauw et al. Arthritis Research & Therapy 2013 15:R88 doi:10.1186/ar4268