Figure 1.

Randomized, placebo-controlled, crossover trial design. Patients were screened for eligibility. Those meeting entry criteria were randomized to one of two treatment sequences: pioglitazone then placebo or placebo then pioglitazone. Patients were assessed every four weeks. Treatment phases were separated by a four-week washout period.

Ormseth et al. Arthritis Research & Therapy 2013 15:R110   doi:10.1186/ar4290
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