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Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy

Herbert SB Baraf*, Michael A Becker, Sergio R Gutierrez-Urena, Edward L Treadwell, Janitzia Vazquez-Mellado, Claudia D Rehrig, Faith D Ottery, John S Sundy and Robert A Yood

Arthritis Research & Therapy 2013, 15:R137  doi:10.1186/ar4318