Analysis of cytokine levels in mice with reduced collagen-induced arthritis. At the end of the therapy 13 different cytokine concentrations were measured in plasma using multiplex bead-based flow cytometry. Data points of cytokine concentrations above detection level are represented in a scatter plot with the mean ± standard error of the mean (n = 10). Standard curves defined with positive control samples (Additional file 5) were used to generate a level of quantification (LOQ; dotted red line). IFN, interferon; IL, interleukin; TNF, tumor necrosis factor.
Doll et al. Arthritis Research & Therapy 2013 15:R138 doi:10.1186/ar4319