Additional file 1: Figure S1.

IL-17 induces fibroblast proliferation and collagen production. (A) Fibroblasts isolated from SSc patients were cultured in 20 ng/ml IL-17 or vehicle for the indicated number of days, and their growth was analyzed by MMT assay. (B) Fibroblasts were cultured in the indicated doses of IL-17 for 48 hours; the gene expression of collagen 1 and collagen 3 was measured by real-time RT-PCR analysis.

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Yang et al. Arthritis Research & Therapy 2014 16:R4   doi:10.1186/ar4430