Rheumatoid arthritis patients exhibit impaired Candida albicans-specific Th17 responses
1 Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
2 Division of Rheumatology & Clinical Immunology, Department of Medicine, University of Pittsburgh, BST S702, 3500 Terrace Street, Pittsburgh, PA 15261, USA
Arthritis Research & Therapy 2014, 16:R50 doi:10.1186/ar4480Published: 11 February 2014
Additional file 1: Figure S1:
(A) IL-17A production under Th17 differentiating conditions correlates with baseline IL-17A production. IL-17A production by PBMC co-cultures with Th17 differentiating cytokines was correlated to baseline IL-17A production by PBMCs by spearman’s coefficient. (B) IL-17 production to HK C. albicans correlates with the fraction of circulating Th17 cells. IL-17A production by PBMCs co-cultured with HK C. albicans was correlated to the fraction of circulating Th17 cells by Spearman’s coefficient.
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