A representative 2D DIGE gel image of JIA synovial membrane proteins. Proteins labeled using fluorescent dyes Cy3 (green) and Cy5 (red). Protein samples were separated on an 11 cm pH4 to 7 IPG strip and on a 12.5% homogenous SDS-PAGE gel. Protein spots analysed by mass spectrometry are highlighted by spot outlines. Spot numbers correspond with those listed in Table 2, Additional file 1: Table S1 and Figure 2. Proteins overexpressed in oligoarticular patients are indicated by red spot outlines; proteins overexpressed in polyarticular are indicated by blue spot outlines. DIGE, difference in-gel electrophoresis; JIA, juvenile idiopathic arthritis.
Finnegan et al. Arthritis Research & Therapy 2014 16:R8 doi:10.1186/ar4434