IgG4 secreting by CD19 + CD24 + CD38- memory B cells from IgG4-related disease patients. Isolated CD19 + CD24 + CD38- memory B cells from IgG4-RD, primary Sjögren’s syndrome (pSS) patients and healthy controls (HC) were cultured in vitro, stimulated with CD40L and CpG ODN 2006. At day 7, the supernatants were collected and IgG4 level was evaluated by CBA. The results are shown in A-C.
Lin et al. Arthritis Research & Therapy 2014 16:R118 doi:10.1186/ar4571