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Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing – a biochemical paradigm for the ageing immune system

Tamàs Fülöp*, Anis Larbi, Gilles Dupuis and Graham Pawelec

Arthritis Res Ther 2003, 5:290-302  doi:10.1186/ar1019