Figure 2.

Scheme showing the pain-modulating pathways in the dorsal horn of the spinal cord. Nociceptive A-delta fibres and nociceptive C fibres cause release of substance P in the dorsal horn. Serotonin released by the dorsolateral inhibitory tracts inhibits the release of substance P.

Gupta and Silman Arthritis Res Ther 2004 6:98-106   doi:10.1186/ar1176
Download authors' original image