Changes in the serum concentrations of (a) antinuclear antibodies (ANAs), (b) anti-double-stranded (ds)DNA antibodies, (c) anticardiolipin (aCL) IgG and (d) aCL IgM in 30 rheumatoid arthritis patients at different times during 78 weeks of infliximab treatment. In the graphs shown in panels b-d the reported values always remained below the upper normal limits, which were 30 IU/ml for anti-dsDNA antibodies, 10 U/ml for IgG aCl and 7 U/ml for IgM aCL. The diamonds indicate median values, and vertical bars indicate the interquartile range.
Bobbio-Pallavicini et al. Arthritis Res Ther 2004 6:R264-R272 doi:10.1186/ar1173