Plot of normalized logarithmic expression signal intensities RNAs from late osteoarthritic against the intensities for normal cartilage. RNA samples from 10 late-stage osteoarthritis patients were hybridized in comparison with normal cartilage (pool of nine donors) on SensiChip microarrays. After normalization, expression data were merged and corresponding signal intensities of late-stage osteoarthritis patients and normal cartilage were plotted against each other. Several differentially expressed marker genes (P < 0.01) are highlighted and diagonal lines indicate a twofold regulation. Error bars show standard deviations of ratios.
Gebauer et al. Arthritis Res Ther 2005 7:R274-R284 doi:10.1186/ar1479