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Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption

David A Young, Rachel L Lakey, Caroline J Pennington, Debra Jones, Lara Kevorkian, Dylan R Edwards, Timothy E Cawston and Ian M Clark*

Arthritis Research & Therapy 2005, 7:R503-R512  doi:10.1186/ar1702