Correlation between serum heme oxygenase (HO)-1 and other serum constituents. (a) Correlation between serum HO-1 and ferritin in the patients with hemophagocytic syndrome (HPS) and adult-onset Still's disease (ASD) at the time when the serum ferritin was highest during the study. P = 0.0048, as determined by multiple regression analyses. (b,c) Correlations between HO-1 and (b) lactate dehydrogenase (LDH), and (c) C-reactive protein (CRP) in the same patients at the same point in the study.
Kirino et al. Arthritis Research & Therapy 2005 7:R616-R624 doi:10.1186/ar1721