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Intra-articular injections of high-molecular-weight hyaluronic acid have biphasic effects on joint inflammation and destruction in rat antigen-induced arthritis

Andreas Roth*, Jürgen Mollenhauer, Andreas Wagner, Reneè Fuhrmann, Albrecht Straub, Rudolf A Venbrocks, Peter Petrow, Rolf Bräuer, Harald Schubert, Jörg Ozegowski, Gundela Peschel, Peter J Müller and Raimund W Kinne

Arthritis Research & Therapy 2005, 7:R677-R686  doi:10.1186/ar1725