Effect of HGF on skin fibrosis in TSK/+ mice. Skin fibrosis was assessed by quantitatively measuring hypodermal thickness. The hypodermal thickness was measured under light microscopy as the thickness of the hypodermis or superficial fascia beneath the panniculus carnosus. Data represent the mean ± standard deviation from six mice (three male mice and three female mice) in each group. *p < 0.05. HGF, hepatocyte growth factor; TSK/+, tight skin.
Iwasaki et al. Arthritis Research & Therapy 2006 8:R161 doi:10.1186/ar2068