Key stages in the process of angiogenesis. This diagram summarizes the steps involved in the formation of new capillary blood vessels. Steps include protease production, endothelial cell migration and proliferation, vascular tube formation, anastomosis of newly formed tubes, synthesis of a new basement membrane and incorporation of pericytes. Reproduced with permission from Lowe et al. Br J Dermatol 1995 © Blackwell Publishing .
Koch and Distler Arthritis Research & Therapy 2007 9(Suppl 2):S3 doi:10.1186/ar2187