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Review   
High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?
Ranjeny Thomas, Malcolm Turner, Andrew P Cope
Arthritis Research & Therapy 2008, 10:210 (24 July 2008)
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Research article    
Brain-derived neurotrophic factor and its receptor in the human and sand rat intervertebral disc
Helen E Gruber, Jane A Ingram, Gretchen L Hoelscher, Natalia Zinchenko, H. JAMES Norton, Edward N. Hanley Jr.
Arthritis Research & Therapy 2008, 10:R82 (17 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Efficacy of fibromyalgia treatment according to level of care: a meta-analysis
Javier Garcia-Campayo, Jesus Magdalena, Rosa Magallon, Esther Fernandez-Garcia, Montserrat Salas, Eva Andres
Arthritis Research & Therapy 2008, 10:R81 (15 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
No evidence of association or interactions between the IL-4, IL-4R alpha and IL-13 genes and rheumatoid arthritis
Ioanna Marinou, Simon H Till, David J Moore, Anthony G Wilson
Arthritis Research & Therapy 2008, 10:R80 (14 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared to age-matched macroscopically normal and control tissues
James Melrose, Emily F Fuller, Peter J Roughley, Margaret M Smith, Briedgeen Kerr, Clare E Hughes, Bruce Caterson, Christopher B Little
Arthritis Research & Therapy 2008, 10:R79 (14 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Ultrasound properties of articular cartilage in the tibio-femoral joint in knee osteoarthritis: relation to clinical assessment (ICRS grade)
Hiroshi Kuroki, Yasuaki Nakagawa, Koji Mori, Masahiko Kobayashi, Ko Yasura, Yukihiro Okamoto, Takashi Suzuki, Kohei Nishitani, Takashi Nakamura
Arthritis Research & Therapy 2008, 10:R78 (13 July 2008)
[Abstract] [Provisional PDF]

Research article    
Low-intensity pulsed ultrasound activates the phosphatidylinositol 3 kinase/Akt pathway and stimulates the growth of chondrocytes in three-dimensional cultures: a basic science study
Ryohei Takeuchi, Akihide Ryo, Noriko Komitsu, Yuko Mikuni-Takagaki, Atsuko Fukui, Yuta Takagi, Toshihiko Shiraishi, Shin Morishita, Yoshiyuki Yamazaki, Ken Kumagai, Ichiro Aoki, Tomoyuki Saito
Arthritis Research & Therapy 2008, 10:R77 (11 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
The renal metallothionein expression profile is altered in human lupus nephritis
Mikkel Faurschou, Milena Penkowa, Claus Bøgelund Andersen, Henrik Starklint, Søren Jacobsen
Arthritis Research & Therapy 2008, 10:R76 (6 July 2008)
[Abstract] [Full text] [PDF]

Research article    
Presence and utility of IgA-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis: the Swedish TIRA project
Anna Svärd, Alf Kastbom, Åsa Reckner-Olsson, Thomas Skogh
Arthritis Research & Therapy 2008, 10:R75 (4 July 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2
Wasim S Khan, Simon R Tew, Adetola B Adesida, Timothy E Hardingham
Arthritis Research & Therapy 2008, 10:R74 (3 July 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis
Pei Jin, Juan Zhang, Percy F Sumariwalla, Irene Ni, Brett Jorgensen, Damian Crawford, Suzanne Phillips, Marc Feldmann, H Michael Shepard, Ewa M Paleolog
Arthritis Research & Therapy 2008, 10:R73 (1 July 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review   
High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease
David S Pisetsky, Helena Erlandsson-Harris, Ulf Andersson
Arthritis Research & Therapy 2008, 10:209 (30 June 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling
Rille Pullerits, Ing-Marie Jonsson, George Kollias, Andrej Tarkowski
Arthritis Research & Therapy 2008, 10:R72 (26 June 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling
Christelle Boileau, Steeve Kwan Tat, Jean-Pierre Pelletier, Saranette Cheng, Johanne Martel-Pelletier
Arthritis Research & Therapy 2008, 10:R71 (25 June 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study
Sella A Provan, Kristin Angel, Sigrid Ødegård, Petter Mowinckel, Dan Atar, Tore K Kvien
Arthritis Research & Therapy 2008, 10:R70 (23 June 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Altered fractalkine cleavage potentially promotes local inflammation in NOD salivary gland
Manon E Wildenberg, Cornelia G van Helden-Meeuwsen, Hemmo A Drexhage, Marjan A Versnel
Arthritis Research & Therapy 2008, 10:R69 (19 June 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
The 5.5-year results of MegaOATS autologous transfer of the posterior femoral condyle: a case-series study
Sepp Braun, Philipp Minzlaff, Regina Hollweck, Klaus Wörtler, Andreas B Imhoff
Arthritis Research & Therapy 2008, 10:R68 (16 June 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Editorial    
Paradoxical effects of tumour necrosis factor- in adjuvant-induced arthritis
Richard O Williams
Arthritis Research & Therapy 2008, 10:113 (6 June 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Editorial    
Gout in the spotlight
Alexander So
Arthritis Research & Therapy 2008, 10:112 (6 June 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
The human anti-IL-1 monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis
Rieke Alten, Hermann Gram, Leo A Joosten, Wim B van den Berg, Joachim Sieper, Siegfrid Wassenberg, Gerd Burmester, Piet van Riel, Maria Diaz-Lorente, Gerardus JM Bruin, Thasia G Woodworth, Christiane Rordorf, Yannik Batard, Andrew M Wright, Thomas Jung
Arthritis Research & Therapy 2008, 10:R67 (5 June 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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